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Issue 17 Understanding Science

The story of CRISPR

CRISPR-Cas9 technology probably needs no special introduction. After all, exactly this system for precise genome editing has started a complete revolution of genetic engineering. Still, the focus of today’s article won’t be the application of CRISPR-Cas9 in biotechnology, no matter how fascinating it gets (but no worries, we will come back to it some other time).

Today, it’s time to take a look at the background of this almost perfect molecular tool, today’s version of which is reduced to only one enzyme and one carefully picked RNA molecule.